ArgR - UniProtKB: G3XCU2 regulon and binding site collection of Pseudomonas aeruginosa PAO1


Sites are listed as curated.

TCGTCTTTCATTTTGGCGACATTGAATTTCATTTTCTCGCCG
GAAAGTTTCAGTTTTGCACCATAAAGATTCATCAATGCGTCA
CGTCTTATTGGTGGACCGGAATGTCGCGATTCTGTAAACTAC
AGGCGCGATCTTATAAGGAAATGTCGCGGAAACACAAGGAGG
CTGCGCCTTCCCGATGCTTTCTGTCGCATTTCCGAAAGCCGC
TTCCTACTCAAAGTAATTAGATGACGCATTCCTGTAAGTCGC
CTTCGGTGCTTTTATAATTAGTTGTCGCATTGAAGAAATAACC
TGTCGCTTTTGCGTCTAAAGCTGTCGCCCCTCTGTAATTTCC
TGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
CGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
CGGCTTGCCCTTGTAAGAAAAGGTCGCGGCAACACAAGTCGG
TGTCCTTTTGTTGAAAAACGACGTCGCAATCAGAACAGTCCG
TGTCGTCGCAGGCGCATTGCCAGCCGGGAGGCCGGAAATCCC
GGTCGCCTCTGCGACATTCGCTGTCGTGTCCCGGCGTGCCGC
TGTCGCATCGCTGCAGTGCGCTGTCGCGTAGGAACAAAACTG
CGCACCTACGCAGATGCGACATGCGTCATGCAATTTTGCGACA
TGACCGACGGCGGCACCTGCGTGTCGCAGAAACGAAA
TGCTCCCGGGGTGAACGAATATGTCGCAGCACGGTAAGTGTT

Sites are listed after the alignment process. For alignment of variable-length binding sites, LASAGNA is used.

GCGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
ATGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
TCGTCTTATTGGTGGACCGGAATGTCGCGATTCTGTAAACTAC
AAGGCGCGATCTTATAAGGAAATGTCGCGGAAACACAAGGAGG
ACTGCGCCTTCCCGATGCTTTCTGTCGCATTTCCGAAAGCCGC
CTTCCTACTCAAAGTAATTAGATGACGCATTCCTGTAAGTCGC
CTTCGGTGCTTTTATAATTAGTTGTCGCATTGAAGAAATAACC
CTGTCGCTTTTGCGTCTAAAGCTGTCGCCCCTCTGTAATTTCC
ATGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
GCGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
GCGGCTTGCCCTTGTAAGAAAAGGTCGCGGCAACACAAGTCGG
CTGTCCTTTTGTTGAAAAACGACGTCGCAATCAGAACAGTCCG
ATGTCGTCGCAGGCGCATTGCCAGCCGGGAGGCCGGAAATCCC
AGGTCGCCTCTGCGACATTCGCTGTCGTGTCCCGGCGTGCCGC
TTGTCGCATCGCTGCAGTGCGCTGTCGCGTAGGAACAAAACTG
TGTCGCAAAATTGCATGACGCATGTCGCATCTGCGTAGGTGCG
ATGACCGACGGCGGCACCTGCGTGTCGCAGAAACGAAAAAGGC
ATGCTCCCGGGGTGAACGAATATGTCGCAGCACGGTAAGTGTT

For the selected transcription factor and species, the list of curated binding sites in the database are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation.

    Genome TF TF conformation Site sequence Site location Experimental techniques Gene regulation Curations PMIDs
    NC_002516.2 G3XCU2 not specified TCGTCTTTCATTTTGGCGACATTGAATTTCATTTTCTCGCCG -[5672265:5672306] Experimental technique details Beta-gal reporter assay - Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) gltB (PA5036) , gltD (PA5035)
    ... ... gltB gltD
    714 15175298
    NC_002516.2 G3XCU2 not specified GAAAGTTTCAGTTTTGCACCATAAAGATTCATCAATGCGTCA -[5138835:5138876] Experimental technique details Beta-gal reporter assay - Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) gdhA (PA4588)
    ... ... gdhA
    714 15175298
    NC_002516.2 G3XCU2 dimer CGTCTTATTGGTGGACCGGAATGTCGCGATTCTGTAAACTAC -[5345028:5345069] Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) carA (PA4758) , PA4758.1 , PA4757 , carB (PA4756) , greA (PA4755) , PA4754
    ... ... carA PA4758.1 PA4757 carB greA PA4754
    720 9286981
    NC_002516.2 G3XCU2 dimer AGGCGCGATCTTATAAGGAAATGTCGCGGAAACACAAGGAGG -[3958882:3958923] Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) argF (PA3537) , PA3536 , PA3538 , PA3539
    ... ... argF PA3536 PA3538 PA3539
    720 9286981
    NC_002516.2 G3XCU2 dimer CTGCGCCTTCCCGATGCTTTCTGTCGCATTTCCGAAAGCCGC +[977755:977796] Experimental technique details Beta-gal reporter assay - Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) - Experimental technique details S1 nuclease protection (ECO:0005666) aruC (PA0895) , PA0894
    ... ... aruC PA0894
    720 9286981
    NC_002516.2 G3XCU2 not specified TTCCTACTCAAAGTAATTAGATGACGCATTCCTGTAAGTCGC -[5820785:5820826] Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Site directed mutagenesis (ECO:0005667) - Experimental technique details Visual sequence inspection (nan) arcC (PA5173) , arcB (PA5172) , arcA (PA5171) , arcD (PA5170)
    ... ... arcC arcB arcA arcD
    966 10198009
    NC_002516.2 G3XCU2 not specified CTTCGGTGCTTTTATAATTAGTTGTCGCATTGAAGAAATAACC +[971962:972004] Experimental technique details Beta-gal reporter assay - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) aotJ (PA0888) , aotQ (PA0889) , aotM (PA0890) , PA0891 , aotP (PA0892) , argR (PA0893) , PA0887.1
    ... ... aotJ aotQ aotM PA0891 aotP argR PA0887.1
    762 9791103
    NC_002516.2 G3XCU2 not specified TGTCGCTTTTGCGTCTAAAGCTGTCGCCCCTCTGTAATTTCC -[3945934:3945975] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) argG (PA3525)
    ... ... argG
    769 15175299
    NC_002516.2 G3XCU2 not specified TGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC +[5138835:5138876] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) gdhA (PA4588)
    ... ... gdhA
    769 15175299
    NC_002516.2 G3XCU2 not specified CGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA +[5672265:5672306] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) gltB (PA5036) , gltD (PA5035)
    ... ... gltB gltD
    769 15175299
    NC_002516.2 G3XCU2 not specified CGGCTTGCCCTTGTAAGAAAAGGTCGCGGCAACACAAGTCGG -[1974698:1974739] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) ldcA (PA1818) , PA1819 , PA1817
    ... ... ldcA PA1819 PA1817
    769 15175299
    NC_002516.2 G3XCU2 not specified TGTCCTTTTGTTGAAAAACGACGTCGCAATCAGAACAGTCCG +[2153248:2153289] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) braZ (PA1971) , PA1972 , pqqF (PA1973)
    ... ... braZ PA1972 pqqF
    769 15175299
    NC_002516.2 G3XCU2 not specified TGTCGTCGCAGGCGCATTGCCAGCCGGGAGGCCGGAAATCCC -[2233778:2233819] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) PA2042 , PA2043
    ... ... PA2042 PA2043
    769 15175299
    NC_002516.2 G3XCU2 not specified GGTCGCCTCTGCGACATTCGCTGTCGTGTCCCGGCGTGCCGC -[4413075:4413116] Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) PA3934
    ... ... PA3934
    769 15175299
    NC_002516.2 G3XCU2 not specified TGTCGCATCGCTGCAGTGCGCTGTCGCGTAGGAACAAAACTG -[5800368:5800409] Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) PA5152 , PA5153 , PA5154 , PA5155
    ... ... PA5152 PA5153 PA5154 PA5155
    769 15175299
    NC_002516.2 G3XCU2 not specified CGCACCTACGCAGATGCGACATGCGTCATGCAATTTTGCGACA -[1045458:1045500] Experimental technique details Consensus search (ECO:0005624) - Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) - Experimental technique details RNA dot blot (ECO:0001177) oprD (PA0958) , PA0959 , PA0960
    ... ... oprD PA0959 PA0960
    768 10464217
    NC_002516.2 G3XCU2 not specified TGACCGACGGCGGCACCTGCGTGTCGCAGAAACGAAA -[4322671:4322707] Experimental technique details Beta-gal reporter assay - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Site directed mutagenesis (ECO:0005667) - Experimental technique details Visual sequence inspection (nan) dauB (PA3862) , dauA (PA3863) , dauR (PA3864)
    ... ... dauB dauA dauR
    770 19850617
    NC_002516.2 G3XCU2 not specified TGCTCCCGGGGTGAACGAATATGTCGCAGCACGGTAAGTGTT -[3441665:3441706] Experimental technique details Beta-gal reporter assay - Experimental technique details Multiple sequence alignment (MSA) (ECO:0005556) - Experimental technique details Visual sequence inspection (nan) gdhB (PA3068) , PA3067 , PA3066 , PA3065
    ... ... gdhB PA3067 PA3066 PA3065
    772 11133942

    All binding sites in split view are combined and a sequence logo is generated. Note that it may contain binding site sequences from different transcription factors and different species. To see individiual sequence logos and curation details go to split view.


    Sites are listed as curated.

    TCGTCTTTCATTTTGGCGACATTGAATTTCATTTTCTCGCCG
    GAAAGTTTCAGTTTTGCACCATAAAGATTCATCAATGCGTCA
    CGTCTTATTGGTGGACCGGAATGTCGCGATTCTGTAAACTAC
    AGGCGCGATCTTATAAGGAAATGTCGCGGAAACACAAGGAGG
    CTGCGCCTTCCCGATGCTTTCTGTCGCATTTCCGAAAGCCGC
    TTCCTACTCAAAGTAATTAGATGACGCATTCCTGTAAGTCGC
    CTTCGGTGCTTTTATAATTAGTTGTCGCATTGAAGAAATAACC
    TGTCGCTTTTGCGTCTAAAGCTGTCGCCCCTCTGTAATTTCC
    TGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
    CGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
    CGGCTTGCCCTTGTAAGAAAAGGTCGCGGCAACACAAGTCGG
    TGTCCTTTTGTTGAAAAACGACGTCGCAATCAGAACAGTCCG
    TGTCGTCGCAGGCGCATTGCCAGCCGGGAGGCCGGAAATCCC
    GGTCGCCTCTGCGACATTCGCTGTCGTGTCCCGGCGTGCCGC
    TGTCGCATCGCTGCAGTGCGCTGTCGCGTAGGAACAAAACTG
    CGCACCTACGCAGATGCGACATGCGTCATGCAATTTTGCGACA
    TGACCGACGGCGGCACCTGCGTGTCGCAGAAACGAAA
    TGCTCCCGGGGTGAACGAATATGTCGCAGCACGGTAAGTGTT

    Sites are listed after the alignment process. For alignment of variable-length binding sites, LASAGNA is used.

    GCGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
    ATGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
    TCGTCTTATTGGTGGACCGGAATGTCGCGATTCTGTAAACTAC
    AAGGCGCGATCTTATAAGGAAATGTCGCGGAAACACAAGGAGG
    ACTGCGCCTTCCCGATGCTTTCTGTCGCATTTCCGAAAGCCGC
    CTTCCTACTCAAAGTAATTAGATGACGCATTCCTGTAAGTCGC
    CTTCGGTGCTTTTATAATTAGTTGTCGCATTGAAGAAATAACC
    CTGTCGCTTTTGCGTCTAAAGCTGTCGCCCCTCTGTAATTTCC
    ATGACGCATTGATGAATCTTTATGGTGCAAAACTGAAACTTTC
    GCGGCGAGAAAATGAAATTCAATGTCGCCAAAATGAAAGACGA
    GCGGCTTGCCCTTGTAAGAAAAGGTCGCGGCAACACAAGTCGG
    CTGTCCTTTTGTTGAAAAACGACGTCGCAATCAGAACAGTCCG
    ATGTCGTCGCAGGCGCATTGCCAGCCGGGAGGCCGGAAATCCC
    AGGTCGCCTCTGCGACATTCGCTGTCGTGTCCCGGCGTGCCGC
    TTGTCGCATCGCTGCAGTGCGCTGTCGCGTAGGAACAAAACTG
    TGTCGCAAAATTGCATGACGCATGTCGCATCTGCGTAGGTGCG
    ATGACCGACGGCGGCACCTGCGTGTCGCAGAAACGAAAAAGGC
    ATGCTCCCGGGGTGAACGAATATGTCGCAGCACGGTAAGTGTT
    Download data in FASTA format.
    Download data in TSV (tab-separated-value) format. For each binding site, all sources of evidence (i.e. experimental techniques and publication information) are combined into one record.
    Download raw data in TSV format. All reported sites are exported individually.
    Download data in Attribute-Relation File Format (ARFF).
    Download Position-Specific-Frequency-Matrix of the motif in TRANSFAC format.
    Download Position-Specific-Frequency-Matrix of the motif in JASPAR format.
    Download Position-Specific-Frequency-Matrix of the motif in raw FASTA format. The matrix consists of four columns in the order A C G T.