Curation Information

Molecular characterization of CcpA and involvement of this protein in transcriptional regulation of lactate dehydrogenase and pyruvate formate-lyase in the ruminal bacterium Streptococcus bovis.;Asanuma N, Yoshii T, Hino T;Applied and environmental microbiology 2004 Sep; 70(9):5244-51 [15345406]
CcpA [A0A0C6FYN7, view regulon]
Reported TF sp.
Streptococcus bovis JB1
Reported site sp.
Streptococcus bovis JB1
Created by
Dinara Sagitova
Curation notes

Experimental Process

A putative CcpA binding site was found in the pepQ-ccpA intergenic region by visual sequence inspection. This sequence differed from the consensus CcpA binding sequence by one nucleotide. EMSA confirmed that CcpA bound specifically to the ccpA promoter region.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... ccpA pepQ MGAS10750_Spy0435 gloA MGAS10750_Spy0433 MGAS10750_Spy0438 MGAS10750_Spy0439
Experimental technique details EMSA (ECO:0001807) - Experimental technique details Visual sequence inspection (nan) - not specified not specified