Curation Information

OmpR negatively regulates expression of invasin in Yersinia enterocolitica.;Brzostek K, Brzóstkowska M, Bukowska I, Karwicka E, Raczkowska A;Microbiology (Reading, England) 2007 Aug; 153(Pt 8):2416-25 [17660406]
OmpR [A1JSH8, view regulon]
Reported TF sp.
Yersinia enterocolitica O:9
Reported site sp.
Yersinia enterocolitica O:9
Created by
Dinara Sagitova
Curation notes

Experimental Process

RT-PCR analysis showed that OmpR represses invasin expression at 25C. inv-lacZ reporter gene fusion confirmed that OmpR negatively regulates inv promoter. EMSAs were done to confirm specific binding of OmpR to its target binding site on the inv promoter.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... invA flgN flgM flhE flhA flhB
Experimental technique details Beta-gal reporter assay - Experimental technique details EMSA (ECO:0001807) - Experimental technique details qRT-PCR [RNA] (ECO:0001808) - repressor not specified