Curation Information

Publication
The BldD protein from Streptomyces coelicolor is a DNA-binding protein.;Elliot MA, Leskiw BK;Journal of bacteriology 1999 Nov; 181(21):6832-5 [10542188]
TF
BldD [Q7AKQ8, view regulon]
Reported TF sp.
Streptomyces coelicolor J1501
Reported site sp.
Streptomyces coelicolor J1501
Created by
Dinara Sagitova
Curation notes
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Experimental Process

EMSA with promoter probes of different length identified in the bldD promoter bound by BldD. DNase I footprinting and hydroxyl radical footprinting further localized BldD binding sites.

Transcription Factor Binding Sites


ACGCAGCAGAGTAACGCTGCGTAACCTCAC
ACGCAGCAGAGTAACGCTGCGTAACCTCAC

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type