Researchers used a consensus search of the CRE box (CcpA binding site) in the pneumoniae genome to compile a list of genes with CRE boxes in the promoter. They then cross-referenced that list with the results (trimmed to only significant results) of a DNA-array that compared wt to a CcpA deletion.
Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.
Site sequence | Regulated genes | Gene diagram | Experimental techniques | TF function | TF type |
---|---|---|---|---|---|
TTTGTAAGCTATTCCAAAC | folA, |
|
repressor | dimer | |
ATTGACAACACTGCCAAAA | pstS, |
|
repressor | dimer | |
ATCGAAAACGATAGCATCA | SPD_1026, |
|
repressor | dimer | |
ATTGTTACCGATCACATTC | SPD_0098, |
|
repressor | dimer |