Curation Information

Publication: Induction of the SOS regulon of Haemophilus influenzae does not affect phase variation rates at tetranucleotide or dinucleotide repeats.;Sweetman WA, Moxon ER, Bayliss CD;Microbiology (Reading, England) 2005 Aug; 151(Pt 8):2751-63 [16079351]
TF: LexA [P44858, view regulon]
Reported TF sp.: Haemphilus influenzae strain RM118
Reported site sp.: Haemphilus influenzae strain RM118
Created by: Erill Lab
Curation notes: -

Experimental Process

Consensus search + validation of expression with Northern analysis

Transcription Factor Binding Sites

Sites reported in the paper
Sites matched in the genome

CTGTACATCAATACAG
CTGGATGTTCGTCCAG

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence	Regulated genes	Gene diagram	Experimental techniques	TF function	TF type
CTGTACATCAATACAG	recA,		Experimental technique details Consensus search (ECO:0005624) Consensus search - ECO:0005624 This is a weak form of in-silico search, in which the consensus sequence for the motif is compared to genomic positions and the number of mismatches (between candidate site and consensus) is used as a measure of site-quality. - Experimental technique details Northern blot (ECO:0005653) Northern blot - ECO:0005653 The northern blot is a technique used in molecular biology research to study gene expression by detection of RNA (or isolated mRNA) in a sample. Northern blotting involves the use of electrophoresis to separate RNA samples by size and detection with a hybridization probe complementary to part of or the entire target sequence. -	repressor	dimer
CTGGATGTTCGTCCAG	ruvA,		Experimental technique details Consensus search (ECO:0005624) Consensus search - ECO:0005624 This is a weak form of in-silico search, in which the consensus sequence for the motif is compared to genomic positions and the number of mismatches (between candidate site and consensus) is used as a measure of site-quality. - Experimental technique details Northern blot (ECO:0005653) Northern blot - ECO:0005653 The northern blot is a technique used in molecular biology research to study gene expression by detection of RNA (or isolated mRNA) in a sample. Northern blotting involves the use of electrophoresis to separate RNA samples by size and detection with a hybridization probe complementary to part of or the entire target sequence. -	repressor	dimer