Curation Information

Publication

The PqrR transcriptional repressor of Pseudomonas aeruginosa transduces redox signals via an iron-containing prosthetic group.;Rungrassamee W, Ryan KC, Maroney MJ, Pomposiello PJ;Journal of bacteriology 2009 Nov; 191(21):6709-21 [19717597]

TF

PqrR [Q9I516, view regulon]

Reported TF sp.

Pseudomonas aeruginosa PAO1

Reported site sp.

Pseudomonas aeruginosa PAO1

Created by

Dinara Sagitova

Curation notes

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Experimental Process

Northern blot results showed that PqrR regulates the expression of the pqrA and pqrC genes. EMSA showed that purified His6-PqrR retarded the mobility of the pqrA-pqrR intergenic region. DNAse I footprinting was used to map the binding sites of PqrR at the pqrA-pqrR intergenic region.

Transcription Factor Binding Sites

• Sites reported in the paper
• Sites matched in the genome

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.