Curation Information

Publication

Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA.;Herbig AF, Helmann JD;Molecular microbiology 2001 Aug; 41(4):849-59 [11532148]

TF

PerR [P71086, view regulon]

Reported TF sp.

Bacillus subtilis subsp. subtilis str. 168

Reported site sp.

Bacillus subtilis subsp. subtilis str. 168

Created by

Dinara Sagitova

Curation notes

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Experimental Process

EMSA validated that PerR bound mrgA promoter region. Furthermore, PerR failed to bind mutant mrgA per boxes. PerR binding site on the mrgA promoter was localized by DNase I footprinting analysis.

Transcription Factor Binding Sites

• Sites reported in the paper
• Sites matched in the genome

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.