Curation Information

Publication

RovA is autoregulated and antagonizes H-NS-mediated silencing of invasin and rovA expression in Yersinia pseudotuberculosis.;Heroven AK, Nagel G, Tran HJ, Parr S, Dersch P;Molecular microbiology 2004 Aug; 53(3):871-88 [15255899]

TF

H-NS [Q6VQX1, view regulon]

Reported TF sp.

Yersinia pseudotuberculosis YPIII

Reported site sp.

Yersinia pseudotuberculosis YPIII

Created by

Erill Lab

Curation notes

-

Experimental Process

EMSA to validate multiple binding sites. Beta-gal assays with deletions in promoter region show H-NS-mediated induction. DNAse footprinting with purified H-NS.

Transcription Factor Binding Sites

• Sites reported in the paper
• Sites matched in the genome

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.