Curation Information

Molecular properties and transcriptional control of the phosphofructokinase and pyruvate kinase genes in a ruminal bacterium, Streptococcus bovis.;Asanuma N, Kanada K, Hino T;Anaerobe 2008 Oct; 14(4):237-41 [18565772]
CcpA [S5RJF3, view regulon]
Reported TF sp.
Streptococcus bovis JB1
Reported site sp.
Streptococcus bovis JB1
Created by
Matthew Coveyou
Curation notes

Experimental Process

qRT-PCR of a ccpA mutant strain revealed a 40% decrease in pyk gene expression compared to the wild type which suggested the role of CcpA as an activator of pyk. This was further supported by the identification of a CRE site in the pyk-pfk promoter region by visual identification

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... KE3_0819 KE3_0820 KE3_0818 KE3_0817 KE3_0816 KE3_0815
Experimental technique details qRT-PCR [RNA] (ECO:0001808) - Experimental technique details Visual sequence inspection (nan) - activator not specified