Curation Information

Transcriptomic and proteomic characterization of the Fur modulon in the metal-reducing bacterium Shewanella oneidensis.;Wan XF, Verberkmoes NC, McCue LA, Stanek D, Connelly H, Hauser LJ, Wu L, Liu X, Yan T, Leaphart A, Hettich RL, Zhou J, Thompson DK;Journal of bacteriology 2004 Dec; 186(24):8385-400 [15576789]
Fur [Q8EFN3, view regulon]
Reported TF sp.
Shewanella oneidensis DSP10
Reported site sp.
Shewanella oneidensis DSP10
Created by
Grace Chandler
Curation notes

Experimental Process

DNA microarray analysis identified genes differentially expressed in the wild-type and the fur mutant strains. qRT-PCR validated Fur-dependent expression of some of the genes identified in the microarray analysis. Motif discovery tools identified a 21 bp Fur binding motif.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... omcA
Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details Motif-discovery (ECO:0005558) - Experimental technique details qRT-PCR [RNA] (ECO:0001808) - repressor dimer