Curation Information

The PqrR transcriptional repressor of Pseudomonas aeruginosa transduces redox signals via an iron-containing prosthetic group.;Rungrassamee W, Ryan KC, Maroney MJ, Pomposiello PJ;Journal of bacteriology 2009 Nov; 191(21):6709-21 [19717597]
PqrR [Q9I516, view regulon]
Reported TF sp.
Pseudomonas aeruginosa PAO1
Reported site sp.
Pseudomonas aeruginosa PAO1
Created by
Dinara Sagitova
Curation notes

Experimental Process

Northern blot results showed that PqrR regulates the expression of the pqrA and pqrC genes. EMSA showed that purified His6-PqrR retarded the mobility of the pqrA-pqrR intergenic region. DNAse I footprinting was used to map the binding sites of PqrR at the pqrA-pqrR intergenic region.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type