Curation Information

Heat and DNA damage induction of the LexA-like regulator HdiR from Lactococcus lactis is mediated by RecA and ClpP.;Savijoki K, Ingmer H, Frees D, Vogensen FK, Palva A, Varmanen P;Molecular microbiology 2003 Oct; 50(2):609-21 [14617183]
HdiR [Q9CG39, view regulon]
Reported TF sp.
Lactococcus lactis subsp. lactis Il1403
Reported site sp.
Lactococcus lactis subsp. lactis Il1403
Created by
Erill Lab
Curation notes

Experimental Process

Site was identified in silico by comparison with the HdiR site confirmed in MG1363. Northern blot shows differential expression when the system is induced with mit-C. EMSA verified that HdiR binds the umuC promote.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... umuC yfiA
Experimental technique details Consensus search (ECO:0005624) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Northern blot (ECO:0005653) - repressor dimer