Curation Information

Global transcriptional response of Caulobacter crescentus to iron availability.;da Silva Neto JF, Lourenço RF, Marques MV;BMC genomics 2013 Aug 13; 14():549 [23941329]
Fur [A0A0H3C2M1, view regulon]
Reported TF sp.
Caulobacter crescentus NA1000
Reported site sp.
Caulobacter crescentus NA1000
Created by
Dinara Sagitova
Curation notes
External databases

Experimental Process

Iron responsive and Fur-regulated genes were identified by performing DNA microarray analysis. MEME-based analysis identified Fur binding motif. Fur-dependent expression was validated by β-galactosidase activity assays. Binding of Fur to its target promoter was confirmed by EMSA.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... CCNA_03155 CCNA_03154 CCNA_03153 CCNA_03152 CCNA_03156 CCNA_03157 CCNA_03158 CCNA_03159 CCNA_03160 CCNA_03161
Experimental technique details Beta-gal reporter assay - Experimental technique details DNA-array expression analysis (ECO:0005525) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Motif-discovery (ECO:0005558) - repressor not specified