Curation Information

Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA.;Herbig AF, Helmann JD;Molecular microbiology 2001 Aug; 41(4):849-59 [11532148]
PerR [P71086, view regulon]
Reported TF sp.
Bacillus subtilis subsp. subtilis str. 168
Reported site sp.
Bacillus subtilis subsp. subtilis str. 168
Created by
Dinara Sagitova
Curation notes

Experimental Process

EMSA validated that PerR bound mrgA promoter region. Furthermore, PerR failed to bind mutant mrgA per boxes. PerR binding site on the mrgA promoter was localized by DNase I footprinting analysis.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type