Curation Information

Bacillus subtilis Fur represses one of two paralogous haem-degrading monooxygenases.;Gaballa A, Helmann JD;Microbiology (Reading, England) 2011 Nov; 157(Pt 11):3221-31 [21873409]
Fur [P54574, view regulon]
Reported TF sp.
Bacillus subtilis subsp. subtilis str. 168
Reported site sp.
Bacillus subtilis subsp. subtilis str. 168
Created by
Dinara Sagitova
Curation notes

Experimental Process

Fur-mediated regulation of the hmoA gene was validated by constructing hmoA–cat–lacZ fusion. EMSA showed that Fur bound with high affinity to the hmoA regulatory region.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type