Role of FIS detected by observation of acapsular phenotype, genomic analysis and complementation. Target genes identified by DNA array. Validation for specific target genes by cloning promoters to Kan resistance cassette. Sites predicted with PSSM search. Expression
Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.
|Site sequence||Regulated genes||Gene diagram||Experimental techniques||TF function||TF type|
|GACCAAAAATAAATC||phyA, hyaE, hexD, hexC, hexB,||
|GATTATATTTTAAAT||phyA, hyaE, hexD, hexC, hexB,||