Curation Information

Expression of canonical SOS genes is not under LexA repression in Bdellovibrio bacteriovorus.;Campoy S, Salvador N, Cortés P, Erill I, Barbé J;Journal of bacteriology 2005 Aug; 187(15):5367-75 [16030231]
LexA [Q6MHM9, view regulon]
Reported TF sp.
Bdellovibrio bacteriovorus HD100
Reported site sp.
Bdellovibrio bacteriovorus HD100
Created by
Erill Lab
Curation notes

Experimental Process

Bd0386 was targeted because it is a RecA homolog, whichi are typically regulated by LexA. EMSA was used to validate binding of purified LexA to target sites. Induction with Mitomycin C was assessed with RT-PCR.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... recA Bd0385 dnaE Bd0383 Bd0382 Bd0387 Bd0388 ogt Bd0390 Bd0391 Bd0392 Bd0393 ace
Experimental technique details EMSA (ECO:0001807) - Experimental technique details qRT-PCR [RNA] (ECO:0001808) - repressor dimer