Curation Information

Genome-wide gene regulation of biosynthesis and energy generation by a novel transcriptional repressor in Geobacter species.;Ueki T, Lovley DR;Nucleic acids research 2010 Jan; 38(3):810-21 [19939938]
HgtR [Q747A3, view regulon]
Reported TF sp.
Geobacter sulfurreducens strain DL1
Reported site sp.
Geobacter sulfurreducens strain DL1
Created by
Erill Lab
Curation notes

Experimental Process

Site identified by EMSA and DNAse footprint with crude extract on gltA promoter. Site has nice dyad symmetry. Site function verified by beta-gal assays coupled with directed mutagenesis. Protein identified by systematic EMSA of putative repressors encoded in G. sulfurreducens on the gltA promoter.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... gltA GSU1105 GSU1104 GSU1103 GSU1107 GSU1108
Experimental technique details Beta-gal reporter assay - Experimental technique details DNAse footprinting (ECO:0005631) - Experimental technique details EMSA (ECO:0001807) - Experimental technique details Visual sequence inspection (nan) - repressor not specified