Curation Information

SOS induction in mycobacteria: analysis of the DNA-binding activity of a LexA-like repressor and its role in DNA damage induction of the recA gene from Mycobacterium smegmatis.;Durbach SI, Andersen SJ, Mizrahi V;Molecular microbiology 1997 Nov; 26(4):643-53 [9427395]
LexA [A0QVY5, view regulon]
Reported TF sp.
Mycobacterium smegmatis str. MC2 155
Reported site sp.
Mycobacterium leprae
Created by
Erill Lab
Curation notes

Experimental Process

Binding demonstrated with EMSA, comparison to previously identified motif and site-directed mutagenesis.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... ML1004 ML1001 ML1002 lexA
Experimental technique details EMSA (ECO:0001807) - Experimental technique details Site directed mutagenesis (ECO:0005667) - Experimental technique details Visual sequence inspection (nan) - repressor dimer