Curation Information

The virulence transcriptional activator AphA enhances biofilm formation by Vibrio cholerae by activating expression of the biofilm regulator VpsT.;Yang M, Frey EM, Liu Z, Bishar R, Zhu J;Infection and immunity 2010 Feb; 78(2):697-703 [19933826]
AphA [H9L4T0, view regulon]
Reported TF sp.
Vibrio cholerae C6706
Reported site sp.
Vibrio cholerae C6706
Created by
Erill Lab
Curation notes

Experimental Process

Detected induced expression, isolated AphA as cause, performed EMSA using multiple fragments, visually detected binding site

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... VCA0952 VCA0953
Experimental technique details EMSA (ECO:0001807) - Experimental technique details Luciferase reporter assay (ECO:0005648) - activator dimer