Iterative refinement of motif. Starts with known LexA genes, builds motif with Gibbs sampling discovery, searches genome. For high scoring sites analyzes expression with RT-PCR. Strongly induced are used in next round of motif discovery.
Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.
|Site sequence||Regulated genes||Gene diagram||Experimental techniques||TF function||TF type|